Safety call over stem cell trips 科学家呼吁注意干细胞安全性
文章来源:未知 文章作者:meng 发布时间:2009-09-04 05:45 字体: [ ]  进入论坛

A clampdown on unproven and potentially unsafe stem cell research is being called for by an expert group.


Stem cells in umbilical cord blood have been used to treat blood disease
Stem cells in umbilical cord blood have been used to treat blood disease

Bionet, a group of expert Chinese and European doctors, lawyers and bioethicists(生物伦理学), says countries throughout the world must develop more effective regulation for this emerging science.

They say desperate patients are being subjected to a huge amount of hype(大肆宣传,炒作) when they travel abroad for treatments.

The only way to counter that is through proper clinical trials, they say.

Professor Nicholas Rose, from the London School of Economics, who led the group, said Bionet's team had talked to physicians in China and Europe because China had now overtaken India as the place where pharmaceutical1 companies were carrying out most of their trials.

They had provided a wealth of anecdotal(轶事的) evidence about their concerns that stem cell research was being moved too rapidly into clinical practice without proper study.

He said: "The key is informed consent(知会同意). Doctors should be able to tell the patient about the short-term and long-term prognosis(预知,预测) and the things we don't know about the risks."


Bionet is recommending that the safety and efficiency of stem cell treatments is investigated through state-of-the-art clinical trials before they are offered to patients.

It also says doctors should be honest about the conditions under which germ cells, embryos2(晶胚) or embryonic3 tissue has been collected.

It also recommends that they should only be imported and used for research if they were collected under conditions which are either similar or equivalent to those in the receiving country.

Nobody should be coerced4(强制,强迫) by unfavourable circumstances or by being dependent on someone to donate cells or tissue for research, banking5 or treatment purposes, Bionet says.

And there should be quality standards for stem cells used in clinical practice.

These should include the bacterial6 and viral contamination applied7 during the production of the stem cells.

China introduced new regulations in May calling for clinical trials before stem cell treatments were offered to patients.

Professor Qui Renzong, vice-president of the ethics8 committee at the Chinese Ministry9 of Health, said: "In China there are about 150 institutions now providing stem cell therapy for diabetes10 through to spinal11(脊髓的) injuries."

Foreign patients were paying an average of $25,000 (£15,434) he said but since the regulations were only recently introduced there was no way of knowing how many foreigners had made trips to China for treatments.

Patient's visits

One patient who did go to China is 39-year-old Brian MacNeill, from Argyll, on the west coast of Scotland.

He sufferers from hereditary12 ataxia(遗传性共济失调), a muscle-wasting neurodegenerative(神经变性的) disease.

Mr MacNeill said: "All I can say about the treatment I had with stem cells in China was that I felt a great benefit after the first lot of four injections, with lots of therapy as well, and good benefit from my second visit about one year later.

"The second visit was needed as I felt some of my symptoms come back after 10 months and now the second visit has lasted around 14 months.

"I now am feeling symptoms come back but cannot afford to go for more stem cells. If I could I would.

"It's better to feel good now when you have an illness than be somebody very unhappy and ill anyway without even trying."

A Department of Health spokesperson said: "Any new therapy or treatment requires carefully controlled and evaluated clinical research before it can be considered safe and effective.

"In the UK, there is strict regulation to ensure that vulnerable patients are not exploited or put at risk.

"When stem cell 'treatments' are based overseas, regulatory oversight13 and jurisdiction14(司法权,审判权) is particularly problematic.

"We take this very seriously and strongly encourage anyone considering participating in overseas stem cell 'research trials' or buying internet treatments to talk to their doctor and follow health guidelines."


1 pharmaceutical f30zR     
  • She has donated money to establish a pharmaceutical laboratory.她捐款成立了一个药剂实验室。
  • We are engaged in a legal tussle with a large pharmaceutical company.我们正同一家大制药公司闹法律纠纷。
2 embryos 0e62a67414ef42288b74539e591aa30a     
n.晶胚;胚,胚胎( embryo的名词复数 )
  • Somatic cells of angiosperms enter a regenerative phase and behave like embryos. 被子植物体细胞进入一个生殖阶段,而且其行为象胚。 来自辞典例句
  • Evolution can explain why human embryos look like gilled fishes. 进化论能够解释为什么人类的胚胎看起来象除去了内脏的鱼一样。 来自辞典例句
3 embryonic 58EyK     
  • It is still in an embryonic stage.它还处于萌芽阶段。
  • The plan,as yet,only exists in embryonic form.这个计划迄今为止还只是在酝酿之中。
4 coerced d9f1e897cffdd8ee96b8978b69159a6b     
v.迫使做( coerce的过去式和过去分词 );强迫;(以武力、惩罚、威胁等手段)控制;支配
  • They were coerced into negotiating a settlement. 他们被迫通过谈判解决。
  • He was coerced into making a confession. 他被迫招供。 来自《简明英汉词典》
5 banking aySz20     
  • John is launching his son on a career in banking.约翰打算让儿子在银行界谋一个新职位。
  • He possesses an extensive knowledge of banking.他具有广博的银行业务知识。
6 bacterial dy5z8q     
  • Bacterial reproduction is accelerated in weightless space. 在失重的空间,细菌繁殖加快了。
  • Brain lesions can be caused by bacterial infections. 大脑损伤可能由细菌感染引起。
7 applied Tz2zXA     
  • She plans to take a course in applied linguistics.她打算学习应用语言学课程。
  • This cream is best applied to the face at night.这种乳霜最好晚上擦脸用。
8 ethics Dt3zbI     
  • The ethics of his profession don't permit him to do that.他的职业道德不允许他那样做。
  • Personal ethics and professional ethics sometimes conflict.个人道德和职业道德有时会相互抵触。
9 ministry kD5x2     
  • They sent a deputation to the ministry to complain.他们派了一个代表团到部里投诉。
  • We probed the Air Ministry statements.我们调查了空军部的记录。
10 diabetes uPnzu     
  • In case of diabetes, physicians advise against the use of sugar.对于糖尿病患者,医生告诫他们不要吃糖。
  • Diabetes is caused by a fault in the insulin production of the body.糖尿病是由体內胰岛素分泌失调引起的。
11 spinal KFczS     
  • After three days in Japan,the spinal column becomes extraordinarily flexible.在日本三天,就已经使脊椎骨变得富有弹性了。
  • Your spinal column is made up of 24 movable vertebrae.你的脊柱由24个活动的脊椎骨构成。
12 hereditary fQJzF     
  • The Queen of England is a hereditary ruler.英国女王是世袭的统治者。
  • In men,hair loss is hereditary.男性脱发属于遗传。
13 oversight WvgyJ     
  • I consider this a gross oversight on your part.我把这件事看作是你的一大疏忽。
  • Your essay was not marked through an oversight on my part.由于我的疏忽你的文章没有打分。
14 jurisdiction La8zP     
  • It doesn't lie within my jurisdiction to set you free.我无权将你释放。
  • Changzhou is under the jurisdiction of Jiangsu Province.常州隶属江苏省。
TAG标签: research safety stem cell