Women 'fight off disease better' 女人“抗疾病能力强一点”
文章来源: 文章作者: 发布时间:2009-05-14 06:45 字体: [ ]  进入论坛

Men really do have an excuse for supposedly being wimpy1 about coughs and colds - their immune systems are not as strong as women's, research suggests.



The weaker sex?

A Canadian study indicates that the female sex hormone2 oestrogen(雌激素) gives women's immune systems added bite at fighting off infection.

Oestrogen seems to counter an enzyme3(酶) which blocks the inflammatory process(炎性过程).

The McGill University study appears in Proceedings4 of the National Academy of Sciences.

The researchers focused on an enzyme called Caspase-12, which is known to put a brake on the inflammatory process, the body's first line of defence against harmful invaders5 such as bacteria and viruses.

They worked on mice that lacked the Caspase-12 gene6, and were thus extremely resistant7 to infection.

The human Caspase-12 gene was implanted into a group of male and female mice, but only the males became more prone8 to infection.

The researchers concluded that oestrogen produced by the female mice blocked the expression of the human Caspase-12 gene.

They were also able to locate the precise place where oestrogen binds9 to the gene in order to block its activity.

Since the experiments were conducted using a human gene, the researchers are confident their work is applicable to humans.

Lead researcher Dr Maya Saleh said: "These results demonstrate that women have a more powerful inflammatory response than men."

The researchers believe women may have evolved a more robust10(强壮的,强健的) immune system because of their key role in producing and nurturing11 young.

Their work raises the possibility of new ways to reinforce the immune system using genetic12 manipulation(处理).

But writing in the journal, the researchers said: "A question remains13: will men be amenable14 to(服从) the idea of being treated with an exclusively female hormone?"

Dr Leslie Knapp, of the University of Cambridge, said there was a substantial body of evidence to show that women were better at fighting infections than men.

She said: "Women are well known to be able to respond more robustly15(粗鲁地) to infections, and to recover more quickly than men.

"In evolutionary16 terms it only takes one male to reproduce with lots of females, but females are much more important in terms of producing offspring."


1 wimpy 2e2007f086bd13eaa7a1217cffa68306     
  • I'd rather have a wimpy kid than a dead one, you know? 你知道么?我宁可要一个懦弱的孩子,也不想要一个死的。 来自互联网
  • I hate wimpy drinker. 我讨厌酒量差的人。 来自互联网
2 hormone uyky3     
  • Hormone implants are used as growth boosters.激素植入物被用作生长辅助剂。
  • This hormone interacts closely with other hormones in the body.这种荷尔蒙与体內其他荷尔蒙紧密地相互作用。
3 enzyme cPozF     
  • Above a certain temperature,the enzyme molecule will become unfolded.超过一定温度,酶分子将会展开。
  • An enzyme that dissolves the fibrin of blood clots.能溶解血凝块中的纤维的酶。
4 proceedings Wk2zvX     
  • He was released on bail pending committal proceedings. 他交保获释正在候审。
  • to initiate legal proceedings against sb 对某人提起诉讼
5 invaders 5f4b502b53eb551c767b8cce3965af9f     
入侵者,侵略者,侵入物( invader的名词复数 )
  • They prepared to repel the invaders. 他们准备赶走侵略军。
  • The family has traced its ancestry to the Norman invaders. 这个家族将自己的世系追溯到诺曼征服者。
6 gene WgKxx     
  • A single gene may have many effects.单一基因可能具有很多种效应。
  • The targeting of gene therapy has been paid close attention.其中基因治疗的靶向性是值得密切关注的问题之一。
7 resistant 7Wvxh     
  • Many pests are resistant to the insecticide.许多害虫对这种杀虫剂有抵抗力。
  • They imposed their government by force on the resistant population.他们以武力把自己的统治强加在持反抗态度的人民头上。
8 prone 50bzu     
  • Some people are prone to jump to hasty conclusions.有些人往往作出轻率的结论。
  • He is prone to lose his temper when people disagree with him.人家一不同意他的意见,他就发脾气。
9 binds c1d4f6440575ef07da0adc7e8adbb66c     
v.约束( bind的第三人称单数 );装订;捆绑;(用长布条)缠绕
  • Frost binds the soil. 霜使土壤凝结。 来自《简明英汉词典》
  • Stones and cement binds strongly. 石头和水泥凝固得很牢。 来自《简明英汉词典》
10 robust FXvx7     
  • She is too tall and robust.她个子太高,身体太壮。
  • China wants to keep growth robust to reduce poverty and avoid job losses,AP commented.美联社评论道,中国希望保持经济强势增长,以减少贫困和失业状况。
11 nurturing d35e8f9c6b6b0f1c54ced7de730a6241     
养育( nurture的现在分词 ); 培育; 滋长; 助长
  • These delicate plants need careful nurturing. 这些幼嫩的植物需要精心培育。
  • The modern conservatory is not an environment for nurturing plants. 这个现代化温室的环境不适合培育植物。
12 genetic PgIxp     
  • It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
  • Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。
13 remains 1kMzTy     
  • He ate the remains of food hungrily.他狼吞虎咽地吃剩余的食物。
  • The remains of the meal were fed to the dog.残羹剩饭喂狗了。
14 amenable pLUy3     
  • His scientific discoveries are amenable to the laws of physics.他在科学上的发现经得起物理定律的检验。
  • He is amenable to counsel.他这人听劝。
15 robustly 507ac3bec7e7c48e608da00e709f9006     
  • These three hormones also robustly stimulated thymidine incorporation and inhibited drug-induced apoptosis. 并且这三种激素有利于胸(腺嘧啶脱氧核)苷掺入和抑制药物诱导的细胞凋亡。 来自互联网
  • The economy is still growing robustly, but inflation, It'seems, is back. 经济依然强劲增长,但是通胀似乎有所抬头。 来自互联网
16 evolutionary Ctqz7m     
  • Life has its own evolutionary process.生命有其自身的进化过程。
  • These are fascinating questions to be resolved by the evolutionary studies of plants.这些十分吸引人的问题将在研究植物进化过程中得以解决。