干预蚊子交配以阻止疟疾传播
文章来源:未知 文章作者:meng 发布时间:2009-12-23 05:59 字体: [ ]  进入论坛
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Scientists believe it may be possible to combat malaria1 by interfering2 with the sex lives of the mosquitoes which spread the disease.

科学家相信通过干涉传播疟疾的蚊子的交配过程就可能战胜疟疾。

Anopheles mosquitoes spread malaria
Anopheles mosquitoes spread malaria

They have shown that the insects can only mate successfully if the male is able to seal his sperm3精液 inside the female using a "mating plug".

Without the plug, fertilisation肥沃,受精 cannot occur, and the animals cannot reproduce.

The Imperial College London study is published in the journal PLoS Biology.

The researchers focused on the species of mosquito primarily主要地,根本上 responsible for the transmission of malaria in Africa - Anopheles gambiae甘比亚虐蚊.

These insects mate only once in their lifetime, so disrupting the reproductive process offers a good way of dramatically reducing their numbers.

When they mate, the male transfers sperm to the female followed by a coagulated凝结 mass of proteins and seminal4 fluids精液 known as a mating plug.

This plug is not found in any other species of mosquito and its role had previously5 been unclear.

But the Imperial team showed it was essential for ensuring sperm is correctly retained保留,保存 in the female's sperm storage organ, from where she can fertilise eggs over the course of her lifetime.

In the lab, the researchers were able to stop successful reproduction by preventing the formation of the plug in males.

Not a simple barrier

Lead researcher Dr Flaminia Catteruccia said: "We have shown that the male mating plug is not a simple barrier to insemination受精,播种 from rival males, as has been previously suggested.

"Instead, we discovered that the plug plays an important role in allowing the female to successfully store sperm in the correct way inside her, and as such is vital for successful reproduction.

"Removing or interfering with the mating plug renders渲染,放弃 copulation交尾,交配 ineffective.

"This discovery could be used to develop new ways of controlling populations of A. gambiae mosquitoes, to limit the spread of malaria."

The researchers stopped the plug forming by knocking out a key enzyme酶 which causes the seminal fluids to coagulate into a gelatinous胶状的 solid mass.

Another weapon

Dr Catteruccia said: "If in the future we can develop an inhibitor抑制剂 that prevents the coagulating enzyme6 doing its job inside male A. gambiae mosquitoes in such a way that can be deployed7 easily in the field - for example in the form of a spray水沫,喷雾 as it is done with insecticides - then we could effectively induce sterility8不毛,不育 in female mosquitoes in the wild.

"This could provide a new way of limiting the population of this species of mosquito, and could be one more weapon in the arsenal9兵工厂,军械库 against malaria."

A team at the International Atomic Energy Agency国际原子能组织 (IAEA) are working on another method to reduce the growth of the mosquito population - using radiation to sterilize消毒,使绝育 male insects.



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1 malaria B2xyb     
n.疟疾
参考例句:
  • He had frequent attacks of malaria.他常患疟疾。
  • Malaria is a kind of serious malady.疟疾是一种严重的疾病。
2 interfering interfering     
adj. 妨碍的 动词interfere的现在分词
参考例句:
  • He's an interfering old busybody! 他老爱管闲事!
  • I wish my mother would stop interfering and let me make my own decisions. 我希望我母亲不再干预,让我自己拿主意。
3 sperm jFOzO     
n.精子,精液
参考例句:
  • Only one sperm fertilises an egg.只有一个精子使卵子受精。
  • In human reproduction,one female egg is usually fertilized by one sperm.在人体生殖过程中,一个精子使一个卵子受精。
4 seminal Qzrwo     
adj.影响深远的;种子的
参考例句:
  • The reforms have been a seminal event in the history of the NHS.这些改革已成为英国国民保健制度史上影响深远的一件大事。
  • The emperor's importance as a seminal figure of history won't be diminished.做为一个开创性历史人物的重要性是不会减弱的。
5 previously bkzzzC     
adv.以前,先前(地)
参考例句:
  • The bicycle tyre blew out at a previously damaged point.自行车胎在以前损坏过的地方又爆开了。
  • Let me digress for a moment and explain what had happened previously.让我岔开一会儿,解释原先发生了什么。
6 enzyme cPozF     
n.酵素,酶
参考例句:
  • Above a certain temperature,the enzyme molecule will become unfolded.超过一定温度,酶分子将会展开。
  • An enzyme that dissolves the fibrin of blood clots.能溶解血凝块中的纤维的酶。
7 deployed 4ceaf19fb3d0a70e329fcd3777bb05ea     
(尤指军事行动)使展开( deploy的过去式和过去分词 ); 施展; 部署; 有效地利用
参考例句:
  • Tanks have been deployed all along the front line. 沿整个前线已部署了坦克。
  • The artillery was deployed to bear on the fort. 火炮是对着那个碉堡部署的。
8 sterility 5a6fe796564ac45f93637ef1db0f8094     
n.不生育,不结果,贫瘠,消毒,无菌
参考例句:
  • A major barrier to interspecific hybridization is sterility in the F1 progeny.种间杂交的主要障碍是F1代的不育性。
  • Sterility is some permanent factor preventing procreation.不育是阻碍生殖的一种永久性因素。
9 arsenal qNPyF     
n.兵工厂,军械库
参考例句:
  • Even the workers at the arsenal have got a secret organization.兵工厂工人暗中也有组织。
  • We must be the great arsenal of democracy.我们必须成为民主的大军火库。
10 sterilize LuwwE     
vt.使不结果实;使绝育;使无效;杀菌,消毒
参考例句:
  • Antiseptic is used to sterilize the skin before giving an injection.杀菌剂被用于在注射前给皮肤消毒。
  • He pricks the blister on his heel with a sterilize needle.他用一根消过毒的针扎破他脚后跟上的水泡。
TAG标签: mosquito malaria sex mating
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