Designed to be attached outside a patient's body, the bioartificial liver is based on human liver cells, according to research findings published in the new issue of international science magazine Cell Research on Friday.

 

In its first clinical use last week, the device saved a 61-year-old woman who was dying from acute liver failure, said Prof. Ding Yitao, a member of the research team, which comprised scientists from the Shanghai Institute for Biological Sciences and doctors from Nanjing Drum Tower Hospital.

 

They are planning more clinical tests in Shanghai and the neighboring cities this year.

 

A bioartificial liver can help recover patients' liver functions and prolong their lives so they can wait for suitable donor¹ livers for a transplant, which is currently the only solution to critical cases.

 

Prof. Ding said Chinese researchers have been using artificial livers since 1998, and earlier devices used liver cells from pigs.

 

"The new device is based on cells taken from human skin, fat or other tissues and reprogrammed into [liver] cells," he said. "It is safer and less likely to cause a rejection² reaction."

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