DNA clue to honey bee deaths 蜜蜂死亡DNA线索被发现
文章来源:未知 文章作者:meng 发布时间:2009-08-25 03:20 字体: [ ]  进入论坛

Scientists say that mass bee deaths may be caused by viruses that disrupt gene1 expression.


Multiple viruses may act together to cause colony <a href=collapse2" width="226" border="0" src="/upimg/090825/4_033150_1.jpg" />
Multiple viruses may act together to cause colony collapse

The team analysed which genes3 were turned on and which were turned off in healthy bees and those from hives with colony collapse disorder4 (CCD).

Since 2006, CCD has caused the catastrophic(悲惨的,灾难的) loss of US bee hives and is implicated5 in bee deaths elsewhere.

Writing in PNAS journal, the team say they used "whole genome microarrays" to compare cells from bees' guts7.

Lead scientist May Berenbaum from the University of Illinois told BBC News that the research was made possible by publication of the bee genome in 2006.

"It's an incredibly useful repository(储藏室) of information which allowed the construction of the microarray - a slide which has all 10,000 bee genes on it," she said.

"We used it to compare colony collapse disorder bees with healthy ones and looked at the differences. There are of course 10,000 genes. So there were a whole lot of differences but we could rule out many of them."

Gut6 feeling

The team concentrated on analysing gene expression from cells in the bees' guts because this is the primary site of pesticide8 detoxification(去毒作用) and immune defence.

Previous theories for CCD have included pesticide poisoning as well as infection and mite9(极小量,小虫) infestation10.

But the team's genetic11 analysis of the bees' guts failed to reveal elevated(高贵的,庄严的) expression of pesticide response genes.

In addition, genes involved in immune response showed no clear expression pattern despite the increased prevalence(传播,流行) of viruses and other pathogens(病原体) in CCD colonies.

What did show up in the guts of the CCD bees was an abundance of fragments from the ribosome(核糖体), a structure which is the cell's protein making factory.

According to the researchers, this finding suggests that protein production is likely to be compromised in bees from CCD hives.

Previous research shows that the viruses that bees carry all attack the ribosome.

Little problem

The microbes in question are known as "picorna-like" viruses. The word derives12 from pico, which means little, and RNA (ribonucleic acid).

"These picorna-like viruses all attack at the same spot," said Professor Berenbaum.

"What they do is to work their way into the ribosome and instead of making honey bee protein they make virus proteins.

"So maybe what's happening is basically the ribosome wears out. So we looked to see if the CCD bees have more of these viruses than healthy bees. And they do.

The viruses in question include "deformed13 wing virus" and "Israeli acute paralysis14 virus".

The scientists believe that if a number of similar picorna-like viruses attack simultaneously15, they may be able to overwhelm the ribosome.

"We talk about a smoking gun. We have the bullet hole!" said May Berenbaum.

"We now need to look for how multiple viruses might interact on the ribosome."

The honey bee is the US's key agricultural pollinator(授花粉器). As such it is worth $14bn to the country's economy.

CCD was first identified in 2006. In the winter of 2007-8 more than a third of US bees were lost.

Similar losses have been reported in Europe, giving rise to fears that CCD is a global problem.


1 gene WgKxx     
  • A single gene may have many effects.单一基因可能具有很多种效应。
  • The targeting of gene therapy has been paid close attention.其中基因治疗的靶向性是值得密切关注的问题之一。
2 collapse aWvyE     
  • The country's economy is on the verge of collapse.国家的经济已到了崩溃的边缘。
  • The engineer made a complete diagnosis of the bridge's collapse.工程师对桥的倒塌做了一次彻底的调查分析。
3 genes 01914f8eac35d7e14afa065217edd8c0     
n.基因( gene的名词复数 )
  • You have good genes from your parents, so you should live a long time. 你从父母那儿获得优良的基因,所以能够活得很长。 来自《简明英汉词典》
  • Differences will help to reveal the functions of the genes. 它们间的差异将会帮助我们揭开基因多种功能。 来自英汉非文学 - 生命科学 - 生物技术的世纪
4 disorder Et1x4     
  • When returning back,he discovered the room to be in disorder.回家后,他发现屋子里乱七八糟。
  • It contained a vast number of letters in great disorder.里面七零八落地装着许多信件。
5 implicated 8443a53107b44913ed0a3f12cadfa423     
  • These groups are very strongly implicated in the violence. 这些组织与这起暴力事件有着极大的关联。 来自《简明英汉词典》
  • Having the stolen goods in his possession implicated him in the robbery. 因藏有赃物使他涉有偷盗的嫌疑。 来自《现代汉英综合大词典》
6 gut MezzP     
  • It is not always necessary to gut the fish prior to freezing.冷冻鱼之前并不总是需要先把内脏掏空。
  • My immediate gut feeling was to refuse.我本能的直接反应是拒绝。
7 guts Yraziv     
v.狼吞虎咽,贪婪地吃,飞碟游戏(比赛双方每组5人,相距15码,互相掷接飞碟);毁坏(建筑物等)的内部( gut的第三人称单数 );取出…的内脏n.勇气( gut的名词复数 );内脏;消化道的下段;肠
  • I'll only cook fish if the guts have been removed. 鱼若已收拾干净,我只需烧一下即可。
  • Barbara hasn't got the guts to leave her mother. 巴巴拉没有勇气离开她妈妈。 来自《简明英汉词典》
8 pesticide OMlxV     
  • The pesticide was spread over the vegetable plot.菜田里撒上了农药。
  • This pesticide is diluted with water and applied directly to the fields.这种杀虫剂用水稀释后直接施用在田里。
9 mite 4Epxw     
  • The poor mite was so ill.可怜的孩子病得这么重。
  • He is a mite taller than I.他比我高一点点。
10 infestation infestation     
  • The premises were treated for cockroach infestation.因蟑螂成灾,这些房屋集中进行了灭蟑活动。
  • Parts of California are suffering from an infestation of oriental fruit flies.加利福尼亚的部分地区正遭受东方果蝇的大肆侵袭。
11 genetic PgIxp     
  • It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
  • Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。
12 derives c6c3177a6f731a3d743ccd3c53f3f460     
v.得到( derive的第三人称单数 );(从…中)得到获得;源于;(从…中)提取
  • English derives in the main from the common Germanic stock. 英语主要源于日耳曼语系。 来自《简明英汉词典》
  • He derives his income from freelance work. 他以自由职业获取收入。 来自《简明英汉词典》
13 deformed iutzwV     
  • He was born with a deformed right leg.他出生时右腿畸形。
  • His body was deformed by leprosy.他的身体因为麻风病变形了。
14 paralysis pKMxY     
  • The paralysis affects his right leg and he can only walk with difficulty.他右腿瘫痪步履维艰。
  • The paralysis affects his right leg and he can only walk with difficulty.他右腿瘫痪步履维艰。
15 simultaneously 4iBz1o     
  • The radar beam can track a number of targets almost simultaneously.雷达波几乎可以同时追着多个目标。
  • The Windows allow a computer user to execute multiple programs simultaneously.Windows允许计算机用户同时运行多个程序。
TAG标签: honey death bee clue DNA