中国自主研发抗癌新药获国际认可
文章来源:未知 文章作者:enread 发布时间:2019-01-10 06:21 字体: [ ]  进入论坛
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China's homegrown drug Sintilimab designed for treating relapsed or refractory1 classic Hodgkin lymphoma has won international recognition, with its clinical trial research published as the cover paper in the January issue of The Lancet Haematology.
 
中国自主研发的用于治疗复发或顽固性霍奇金淋巴瘤的药物信迪利单抗获得国际认可,其临床试验研究刊登在一月《柳叶刀血液学》封面上。
 
 
Hodgkin lymphoma is a rare malignant2 lymphoma that occurs mostly in young people between the ages of 20 and 40. Although the cure rate of early treatment is high, patients have a 20 percent chance of recurrence3 after their first treatment. Patients with relapsed or refractory classic Hodgkin lymphoma lack effective treatment in China.
 
Sintilimab, an anti-PD-1 drug, is a kind of checkpoint inhibitor, an emerging anti-cancer therapeutic4 modality that boosts the immune system to help the body target and kill tumors.
 
Professor Shi Yuankai from the Cancer Hospital, Chinese Academy of Medical Sciences, led the clinical research, which enrolled5 96 patients with relapsed or refractory classic Hodgkin's lymphoma from 18 hospitals in China.
 
Results showed that Sintilimab has favorable activity and acceptable toxicity6 in Chinese patients with relapsed or refractory classical Hodgkin lymphoma, with 80.4 percent of the patients showing an objective response.
 
Stephen M Ansell from the Division of Hematology at the Mayo Clinic commented that Sintilimab is a "highly effective treatment which potentially improves the outcomes of patients with classical Hodgkin lymphoma worldwide."


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1 refractory GCOyK     
adj.倔强的,难驾驭的
参考例句:
  • He is a very refractory child.他是一个很倔强的孩子。
  • Silicate minerals are characteristically refractory and difficult to break down.硅酸盐矿物的特点是耐熔和难以分离。
2 malignant Z89zY     
adj.恶性的,致命的;恶意的,恶毒的
参考例句:
  • Alexander got a malignant slander.亚历山大受到恶意的诽谤。
  • He started to his feet with a malignant glance at Winston.他爬了起来,不高兴地看了温斯顿一眼。
3 recurrence ckazKP     
n.复发,反复,重现
参考例句:
  • More care in the future will prevent recurrence of the mistake.将来的小心可防止错误的重现。
  • He was aware of the possibility of a recurrence of his illness.他知道他的病有可能复发。
4 therapeutic sI8zL     
adj.治疗的,起治疗作用的;对身心健康有益的
参考例句:
  • Therapeutic measures were selected to fit the patient.选择治疗措施以适应病人的需要。
  • When I was sad,music had a therapeutic effect.我悲伤的时候,音乐有治疗效力。
5 enrolled ff7af27948b380bff5d583359796d3c8     
adj.入学登记了的v.[亦作enrol]( enroll的过去式和过去分词 );登记,招收,使入伍(或入会、入学等),参加,成为成员;记入名册;卷起,包起
参考例句:
  • They have been studying hard from the moment they enrolled. 从入学时起,他们就一直努力学习。 来自《简明英汉词典》
  • He enrolled with an employment agency for a teaching position. 他在职业介绍所登了记以谋求一个教师的职位。 来自《简明英汉词典》
6 toxicity InYwc     
n.毒性,毒力
参考例句:
  • The hoarse grunt or squeal is characteristic of toxicity.嘶哑的哼声和叫声是中毒的特征。
  • Dieldrin is related to aldrin,and its toxicity to earthworms is similar.狄氏剂与艾氏剂有关,对蚯蚓的毒性是相似的。
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