There may be a very good reason that people naturally clutch（抓住，紧握） their hand after receiving an injury. A new report published online on September 23 in Current Biology shows that self-touch offers significant relief for acute pain（剧烈的疼痛） under experimental conditions. The researchers suggest that the relief comes from a change in the brain's representation of the rest of the body. "Pain is quite an important, but also complicated, experience and can be caused in many different ways," said Patrick Haggard of University College London. "We show that levels of acute pain depend not just on the signals sent to the brain, but also on how the brain integrates these signals into a coherent representation of the body as a whole."

Haggard and his colleague Marjolein Kammers, also of University College London, made the discovery by studying the effects of self-touch in people who were made to feel pain using an experimental condition known as the thermal¹ grill² illusion (TGI). "The TGI is one of the best-established laboratory methods for studying pain perception," Haggard explained. "In our version, the index and ring fingers are placed in warm water and the middle finger in cold water. This generates a paradoxical（矛盾的） feeling that the middle finger is painfully hot." That's ideal because it allows scientists to study the experience of pain without actually causing any injury to those who participate in the studies.

When TGI was induced in an individual's two hands and then the three fingers of one hand were touched to the same fingers on the other hand immediately afterwards, the painful heat experienced by the middle finger dropped by 64 percent compared to a condition without self-touch. That relief didn't come when only one hand was placed under TGI conditions. Partial self-touch in which only one or two fingers were pressed against each other didn't work either. Nor did it work to press the affected⁴ hand against an experimenter's hand that had also been warmed and cooled in the same way.

"In sum," the researchers wrote, "TGI was reduced only when thermosensory and tactile⁵（触觉的） information from all three fingers was fully³ integrated. That is, TGI reduction required a highly coherent somatosensory（躯体感觉的） pattern, including coherence⁶（一致，连贯性） between tactile and thermal patterns and coherence of stimuli⁷ between the two hands."

Haggard said that earlier studies of chronic⁸ pain had suggested the importance of body representation in the experience of pain. For example, the phantom⁹（幽灵的，幻觉的） pain that is often felt following amputation¹⁰（截肢，切断） of a limb appears to lessen¹¹ with time as the brain converges¹²（聚合，会聚） on an updated representation of the body. Haggard said the new findings extend the important role of body representation to acute pain and may lead to a better understanding of the brain mechanisms¹³ involved in chronic pain as well.

The findings might be put to practical use, the researchers say. "Our work suggests that therapies aimed at strengthening the multisensory representation of the body may be effective in reducing pain," Haggard said.