用干细胞再生新头发
文章来源:未知 文章作者:enread 发布时间:2015-01-28 06:38 字体: [ ]  进入论坛
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In a new study from Sanford-Burnham Medical Research Institute (Sanford-Burnham), researchers have used human pluripotent stem cells to generate new hair. The study represents the first step toward the development of a cell-based treatment for people with hair loss. In the United States alone, more than 40 million men and 21 million women are affected1 by hair loss. The research was published online in PLOS One yesterday. "We have developed a method using human pluripotent stem cells to create new cells capable of initiating2 human hair growth. The method is a marked improvement over current methods that rely on transplanting existing hair follicles from one part of the head to another," said Alexey Terskikh, Ph.D., associate professor in the Development, Aging, and Regeneration Program at Sanford-Burnham. "Our stem cell method provides an unlimited3 source of cells from the patient for transplantation and isn't limited by the availability of existing hair follicles."
 
The research team developed a protocol4 that coaxed5 human pluripotent stem cells to become dermal6 papilla cells. They are a unique population of cells that regulate hair-follicle formation and growth cycle. Human dermal papilla cells on their own are not suitable for hair transplants because they cannot be obtained in necessary amounts and rapidly lose their ability to induce hair-follicle formation in culture.
 
"In adults, dermal papilla cells cannot be readily amplified7 outside of the body and they quickly lose their hair-inducing properties," said Terskikh. "We developed a protocol to drive human pluripotent stem cells to differentiate8 into dermal papilla cells and confirmed their ability to induce hair growth when transplanted into mice."
 
"Our next step is to transplant human dermal papilla cells derived9 from human pluripotent stem cells back into human subjects," said Terskikh. "We are currently seeking partnerships10 to implement11 this final step."


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1 affected TzUzg0     
adj.不自然的,假装的
参考例句:
  • She showed an affected interest in our subject.她假装对我们的课题感到兴趣。
  • His manners are affected.他的态度不自然。
2 initiating 88832d3915125bdffcc264e1cdb71d73     
v.开始( initiate的现在分词 );传授;发起;接纳新成员
参考例句:
  • He is good at initiating projects but rarely follows through with anything. 他善于创建项目,但难得坚持完成。 来自《简明英汉词典》
  • Only the perchlorate shows marked sensitiveness and possibly initiating properties. 只有高氯酸盐表现有显著的感度和可能具有起爆性能。 来自辞典例句
3 unlimited MKbzB     
adj.无限的,不受控制的,无条件的
参考例句:
  • They flew over the unlimited reaches of the Arctic.他们飞过了茫茫无边的北极上空。
  • There is no safety in unlimited technological hubris.在技术方面自以为是会很危险。
4 protocol nRQxG     
n.议定书,草约,会谈记录,外交礼节
参考例句:
  • We must observe the correct protocol.我们必须遵守应有的礼仪。
  • The statesmen signed a protocol.那些政治家签了议定书。
5 coaxed dc0a6eeb597861b0ed72e34e52490cd1     
v.哄,用好话劝说( coax的过去式和过去分词 );巧言骗取;哄劝,劝诱
参考例句:
  • She coaxed the horse into coming a little closer. 她哄着那匹马让它再靠近了一点。
  • I coaxed my sister into taking me to the theatre. 我用好话哄姐姐带我去看戏。 来自《现代汉英综合大词典》
6 dermal 3305e4eaa5234975a62da55e3bdc20d9     
adj.皮肤的,真皮的
参考例句:
  • Dermal hypersensitivity usually does not develop until three to four weeks after onset. 皮肤过敏通常在起病后三、四周内不会出现。 来自辞典例句
  • The doctor said permanent dermal pigmentation is a form of microsurgery. 医生说永久的皮肤染色是一种显微手术。 来自互联网
7 amplified d305c65f3ed83c07379c830f9ade119d     
放大,扩大( amplify的过去式和过去分词 ); 增强; 详述
参考例句:
  • He amplified on his remarks with drawings and figures. 他用图表详细地解释了他的话。
  • He amplified the whole course of the incident. 他详述了事件的全过程。
8 differentiate cm3yc     
vi.(between)区分;vt.区别;使不同
参考例句:
  • You can differentiate between the houses by the shape of their chimneys.你可以凭借烟囱形状的不同来区分这两幢房子。
  • He never learned to differentiate between good and evil.他从未学会分辨善恶。
9 derived 6cddb7353e699051a384686b6b3ff1e2     
vi.起源;由来;衍生;导出v.得到( derive的过去式和过去分词 );(从…中)得到获得;源于;(从…中)提取
参考例句:
  • Many English words are derived from Latin and Greek. 英语很多词源出于拉丁文和希腊文。 来自《简明英汉词典》
  • He derived his enthusiasm for literature from his father. 他对文学的爱好是受他父亲的影响。 来自《简明英汉词典》
10 partnerships ce2e6aff420d72bbf56e8077be344bc9     
n.伙伴关系( partnership的名词复数 );合伙人身份;合作关系
参考例句:
  • Partnerships suffer another major disadvantage: decision-making is shared. 合伙企业的另一主要缺点是决定要由大家来作。 来自英汉非文学 - 政府文件
  • It involved selling off limited partnerships. 它涉及到售出有限的合伙权。 来自辞典例句
11 implement WcdzG     
n.(pl.)工具,器具;vt.实行,实施,执行
参考例句:
  • Don't undertake a project unless you can implement it.不要承担一项计划,除非你能完成这项计划。
  • The best implement for digging a garden is a spade.在花园里挖土的最好工具是铁锹。
TAG标签: cells hair stem
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