科学家发现细胞运动新形式
文章来源:未知 文章作者:enread 发布时间:2014-09-01 06:56 字体: [ ]  进入论坛
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For decades, researchers have used petri dishes(培养皿) to study cell movement. These classic tissue culture tools, however, only permit two-dimensional movement, very different from the three-dimensional movements that cells make in a human body. In a new study from the University of Pennsylvania and National Institute of Dental and Craniofacial Research, scientists used an innovative1 technique to study how cells move in a three-dimensional matrix, similar to the structure of certain tissues, such as the skin. They discovered an entirely2 new type of cell movement whereby the nucleus3 helps propel cells through the matrix like a piston4(活塞) in an engine, generating pressure that thrusts the cell's plasma5 membrane6 forward.
 
"Our work elucidated7 a highly intriguing8 question: how cells move when they are in the complex and physiologically10 relevant environment of a 3-D extracellular matrix," said Hyun (Michel) Koo, a professor in the Department of Orthodontics at Penn's School of Dental Medicine. "We discovered that the nucleus can act as a piston that physically11 compartmentalizes the cell cytoplasm(细胞质) and increases the hydrostatic(流体静力学的) pressure driving the cell motility within a 3-D matrix."
 
Koo worked with lead author Ryan Petrie and senior author Kenneth Yamada, both of the National Institutes of Health's NIDCR, on the study, which is published this week in Science.
 
"We think it's a very important normal physiological9 mechanism12 of cell movement that has not been characterized previously," Petrie said.


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1 innovative D6Vxq     
adj.革新的,新颖的,富有革新精神的
参考例句:
  • Discover an innovative way of marketing.发现一个创新的营销方式。
  • He was one of the most creative and innovative engineers of his generation.他是他那代人当中最富创造性与革新精神的工程师之一。
2 entirely entirely     
ad.全部地,完整地;完全地,彻底地
参考例句:
  • The fire was entirely caused by their neglect of duty. 那场火灾完全是由于他们失职而引起的。
  • His life was entirely given up to the educational work. 他的一生统统献给了教育工作。
3 nucleus avSyg     
n.核,核心,原子核
参考例句:
  • These young people formed the nucleus of the club.这些年轻人成了俱乐部的核心。
  • These councils would form the nucleus of a future regime.这些委员会将成为一个未来政权的核心。
4 piston w2Rz7     
n.活塞
参考例句:
  • They use a piston engine instead.他们改用活塞发动机。
  • The piston moves by steam pressure.活塞在蒸汽压力下运动。
5 plasma z2xzC     
n.血浆,细胞质,乳清
参考例句:
  • Keep some blood plasma back for the serious cases.留一些血浆给重病号。
  • The plasma is the liquid portion of blood that is free of cells .血浆是血液的液体部分,不包含各种细胞。
6 membrane H7ez8     
n.薄膜,膜皮,羊皮纸
参考例句:
  • A vibrating membrane in the ear helps to convey sounds to the brain.耳膜的振动帮助声音传送到大脑。
  • A plastic membrane serves as selective diffusion barrier.一层塑料薄膜起着选择性渗透屏障的作用。
7 elucidated dffaae1f65de99f6b0547d9558544eaa     
v.阐明,解释( elucidate的过去式和过去分词 )
参考例句:
  • He elucidated a point of grammar. 他解释了一个语法要点。
  • The scientist elucidated his theory by three simple demonstrations. 这位科学家以三个简单的实例来说明他的理论。 来自《简明英汉词典》
8 intriguing vqyzM1     
adj.有趣的;迷人的v.搞阴谋诡计(intrigue的现在分词);激起…的好奇心
参考例句:
  • These discoveries raise intriguing questions. 这些发现带来了非常有趣的问题。
  • It all sounds very intriguing. 这些听起来都很有趣。 来自《简明英汉词典》
9 physiological aAvyK     
adj.生理学的,生理学上的
参考例句:
  • He bought a physiological book.他买了一本生理学方面的书。
  • Every individual has a physiological requirement for each nutrient.每个人对每种营养成分都有一种生理上的需要。
10 physiologically QNfx3     
ad.生理上,在生理学上
参考例句:
  • Therefore, the liver and gallbladder cannot be completely separated physiologically and pathologically. 因此,肝胆在生理和病理上不能完全分离。
  • Therefore, the liver and gallbladder are closely related physiologically and pathologically. 因此,肝胆在生理和病理上紧密联系。
11 physically iNix5     
adj.物质上,体格上,身体上,按自然规律
参考例句:
  • He was out of sorts physically,as well as disordered mentally.他浑身不舒服,心绪也很乱。
  • Every time I think about it I feel physically sick.一想起那件事我就感到极恶心。
12 mechanism zCWxr     
n.机械装置;机构,结构
参考例句:
  • The bones and muscles are parts of the mechanism of the body.骨骼和肌肉是人体的组成部件。
  • The mechanism of the machine is very complicated.这台机器的结构是非常复杂的。
TAG标签: movement tissue cell
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