新方法手术切除咽喉肿瘤修复气管功能
文章来源:未知 文章作者:enread 发布时间:2011-01-31 03:00 字体: [ ]  进入论坛
(单词翻译:双击或拖选)

Using a novel surgical1 approach, it's possible to rebuild the trachea(气管) and preserve a patient's voice after removing an invasive throat tumor2, according to a new report from Henry Ford3 Hospital in Detroit. This case study is the first of its kind to not only document a successful technique to create a fully4 functional5 trachea, or windpipe, but also report a rare type of malignant6 tumor in an adult's trachea. Most commonly, this type of tumor is seen in newborns and very rarely occurs in the neck, says lead study author Samer Al-Khudari, M.D., with the Department of Otolaryngology-Head & Neck Surgery at Henry Ford Hospital.

"In this case, the patient's tumor had spread to the trachea, thyroid gland7(甲状腺) , muscles around the thyroid gland and nerves in the area," says Dr. Al-Khudari.

According to head and neck cancer surgeon Tamer A. Ghanem, M.D., Ph.D., who led the Henry Ford surgical team, the easiest approach would have been to remove the trachea and the voice box, given the tumor's proximity8 to the larynx(喉) and other surrounding structures. With this method, however, the patient would no longer be able to speak or swallow normally.

Instead, the surgical team took another approach. Using tissue and bone from the patient's arm, they were able to reconstruct the trachea, restoring airflow through the trachea and saving the patient's voice.

"We had to think outside the box to not only safely remove the tumor, but to allow for optimum(最适宜的) functional outcome," says Dr. Ghanem, director of the Head and Neck Oncology & Microvascular Surgery Division at Henry Ford. "This is the first time such a large portion of a patient's trachea has been removed and rebuilt in a way that allows it to be fully functional."

This unique case will be presented Jan. 29 at the poster session for the Triological Society's Combined Section Meeting in Scottsdale, Ariz.

The case study is centered on a 27 year-old man who had a large mass blocking 90 percent of his airway9, making it very difficult for him to breathe.

After a biopsy(活组织检查) and other tests, Henry Ford doctors determined10 the mass was a malignant immature11 teratoma – a cancerous tumor that was quickly spreading throughout the areas of the patient's trachea and surrounding structures.

Such tumors are extremely rare; since the first reported case in 1854, there have only been 300 other reported cases.

With the Henry Ford patient, surgeons first removed the tumor and about half of the patient's airway, just below the voice box.

Using bone and skin from the patient's arm and two titanium plates, surgeon's reconstructed the airway, providing it with full coverage12 and allowing it to be fully functional.

Reconstruction13 of the trachea is challenging, due to the structural14 complexity15 and unique properties of the airway. The ideal reconstruction must not collapse16 during respiration17(呼吸) and have some degree of mobility18 to allow for neck movement.

Currently the patient is using a tracheostomy tube – a tube that is inserted into an opening in the trachea to assist with breathing – but the surgeons do not expect it to be permanent. The patient, however, is able to speak and swallow normally. He also underwent chemotherapy(化学疗法) as part of his treatment.



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1 surgical 0hXzV3     
adj.外科的,外科医生的,手术上的
参考例句:
  • He performs the surgical operations at the Red Cross Hospital.他在红十字会医院做外科手术。
  • All surgical instruments must be sterilised before use.所有的外科手术器械在使用之前,必须消毒。
2 tumor fKxzm     
n.(肿)瘤,肿块(英)tumour
参考例句:
  • He was died of a malignant tumor.他死于恶性肿瘤。
  • The surgeons irradiated the tumor.外科医生用X射线照射那个肿瘤。
3 Ford KiIxx     
n.浅滩,水浅可涉处;v.涉水,涉过
参考例句:
  • They were guarding the bridge,so we forded the river.他们驻守在那座桥上,所以我们只能涉水过河。
  • If you decide to ford a stream,be extremely careful.如果已决定要涉过小溪,必须极度小心。
4 fully Gfuzd     
adv.完全地,全部地,彻底地;充分地
参考例句:
  • The doctor asked me to breathe in,then to breathe out fully.医生让我先吸气,然后全部呼出。
  • They soon became fully integrated into the local community.他们很快就完全融入了当地人的圈子。
5 functional 5hMxa     
adj.为实用而设计的,具备功能的,起作用的
参考例句:
  • The telephone was out of order,but is functional now.电话刚才坏了,但现在可以用了。
  • The furniture is not fancy,just functional.这些家具不是摆着好看的,只是为了实用。
6 malignant Z89zY     
adj.恶性的,致命的;恶意的,恶毒的
参考例句:
  • Alexander got a malignant slander.亚历山大受到恶意的诽谤。
  • He started to his feet with a malignant glance at Winston.他爬了起来,不高兴地看了温斯顿一眼。
7 gland qeGzu     
n.腺体,(机)密封压盖,填料盖
参考例句:
  • This is a snake's poison gland.这就是蛇的毒腺。
  • Her mother has an underactive adrenal gland.她的母亲肾上腺机能不全。
8 proximity 5RsxM     
n.接近,邻近
参考例句:
  • Marriages in proximity of blood are forbidden by the law.法律规定禁止近亲结婚。
  • Their house is in close proximity to ours.他们的房子很接近我们的。
9 airway xzez8W     
n.空中航线,通风口
参考例句:
  • Lay them on their side and ensure the airway is unobstructed.让他们侧躺着,并确保呼吸道畅通。
  • There is a purple airway in London Airport.伦敦机场里有一条皇家专用飞机跑道。
10 determined duszmP     
adj.坚定的;有决心的
参考例句:
  • I have determined on going to Tibet after graduation.我已决定毕业后去西藏。
  • He determined to view the rooms behind the office.他决定查看一下办公室后面的房间。
11 immature Saaxj     
adj.未成熟的,发育未全的,未充分发展的
参考例句:
  • Tony seemed very shallow and immature.托尼看起来好像很肤浅,不夠成熟。
  • The birds were in immature plumage.这些鸟儿羽翅未全。
12 coverage nvwz7v     
n.报导,保险范围,保险额,范围,覆盖
参考例句:
  • There's little coverage of foreign news in the newspaper.报纸上几乎没有国外新闻报道。
  • This is an insurance policy with extensive coverage.这是一项承保范围广泛的保险。
13 reconstruction 3U6xb     
n.重建,再现,复原
参考例句:
  • The country faces a huge task of national reconstruction following the war.战后,该国面临着重建家园的艰巨任务。
  • In the period of reconstruction,technique decides everything.在重建时期,技术决定一切。
14 structural itXw5     
adj.构造的,组织的,建筑(用)的
参考例句:
  • The storm caused no structural damage.风暴没有造成建筑结构方面的破坏。
  • The North American continent is made up of three great structural entities.北美大陆是由三个构造单元组成的。
15 complexity KO9z3     
n.复杂(性),复杂的事物
参考例句:
  • Only now did he understand the full complexity of the problem.直到现在他才明白这一问题的全部复杂性。
  • The complexity of the road map puzzled me.错综复杂的公路图把我搞糊涂了。
16 collapse aWvyE     
vi.累倒;昏倒;倒塌;塌陷
参考例句:
  • The country's economy is on the verge of collapse.国家的经济已到了崩溃的边缘。
  • The engineer made a complete diagnosis of the bridge's collapse.工程师对桥的倒塌做了一次彻底的调查分析。
17 respiration us7yt     
n.呼吸作用;一次呼吸;植物光合作用
参考例句:
  • They tried artificial respiration but it was of no avail.他们试做人工呼吸,可是无效。
  • They made frequent checks on his respiration,pulse and blood.他们经常检查他的呼吸、脉搏和血液。
18 mobility H6rzu     
n.可动性,变动性,情感不定
参考例句:
  • The difference in regional house prices acts as an obstacle to mobility of labour.不同地区房价的差异阻碍了劳动力的流动。
  • Mobility is very important in guerrilla warfare.机动性在游击战中至关重要。
TAG标签: voice tumor trachea
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