利用光声学鉴别黑色素瘤以发现癌症
文章来源:未知 文章作者:meng 发布时间:2010-02-24 03:29 字体: [ ]  进入论坛
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Knowing the stage of a patient's melanoma(黑素瘤,胎记瘤) is important when choosing the best course of treatment. When the cancer has progressed to the lymph nodes(淋巴结) , a more aggressive treatment is needed. Examining an entire lymph node for cancer takes much effort and time; a new technique might help make the process more efficient. University of Missouri researchers in the Christopher S. Bond Life Sciences Center are studying how photoacoustics, or a laser-induced ultrasound, could help scientists locate the general area of the lymph node where melanoma cells could be residing. This new technology could help doctors identify the stage of melanoma with more accuracy. "This method can be used to determine if the cancer has spread from stage 2, where the melanoma is still just in the skin lesion(皮肤损害) , to stage 3, where the melanoma has spread to the lymph nodes," said John Viator, assistant professor in the Department of Biological Engineering and Department of Dermatology . "If the cancer is still at stage 2, a simple procedure can remove that lesion. If the cancer has progressed from the initial skin lesion into the lymphatic(淋巴的) region and possibly the bloodstream, doctors have to make serious decisions about patient care. The cancer may have possibly spread to other organs, such as the liver, lungs or brain."

Currently, pathologists(病理学家) must perform several specific and detailed1 tests to determine if there is cancer in the lymph nodes. This new technology could make the search less time-consuming by identifying a general area of the lymph node that might contain cancer.

"It's very similar to identifying a prize inside a cake," Viator said. "Instead of looking through the entire cake, we can use our ultrasound to pinpoint2 a slice or two that might contain the 'prize.' In the case of the lymph nodes, when you get a signal, this alerts the pathologist that this is an area of the node that might contain cancer cells. At that point, a pathologist would be able to narrow down(限制,缩小) the search, saving time and money."

In the photoacoustic method, a tabletop device scans a lymph node biopsy(活组织检查) with laser pulses. About 95 percent of melanoma cells contain melanin, the pigment3(颜料,色素) that gives skin its color, so they react to the laser's beam, absorbing the light. The laser causes the cells to heat and cool rapidly, which makes them expand and contract. This produces a popping noise that special sensors4 can detect. This method would examine the entire biopsy and identify the general area of the node that has cancer, giving pathologists a better idea of where to look for the cancer.

"This method is quicker and simpler and could be used to improve the efficiency of how doctors determine if the cancer has spread from the original skin lesion into the lymphatic system," Viator said. "This technology could be an important tool in our fight against cancer."

In the study, Viator took human cancer cells and placed them inside canine5 lymph nodes. Then, using the laser, he determined6 the best ways to locate the cancer cells. The next step is to try the procedure using human lymph nodes.



点击收听单词发音收听单词发音  

1 detailed xuNzms     
adj.详细的,详尽的,极注意细节的,完全的
参考例句:
  • He had made a detailed study of the terrain.他对地形作了缜密的研究。
  • A detailed list of our publications is available on request.我们的出版物有一份详细的目录备索。
2 pinpoint xNExL     
vt.准确地确定;用针标出…的精确位置
参考例句:
  • It is difficult to pinpoint when water problems of the modern age began.很难准确地指出,现代用水的问题是什么时候出现的。
  • I could pinpoint his precise location on a map.我能在地图上指明他的准确位置。
3 pigment gi0yg     
n.天然色素,干粉颜料
参考例句:
  • The Romans used natural pigments on their fabrics and walls.古罗马人在织物和墙壁上使用天然颜料。
  • Who thought he might know what the skin pigment phenomenon meant.他自认为可能知道皮肤色素出现这种现象到底是怎么回事。
4 sensors 029aee483db9ae244d7a5cb353e74602     
n.传感器,灵敏元件( sensor的名词复数 )
参考例句:
  • There were more than 2000 sensors here. 这里装有两千多个灵敏元件。 来自《简明英汉词典》
  • Significant changes have been noted where sensors were exposed to trichloride. 当传感器暴露在三氯化物中时,有很大变化。 来自辞典例句
5 canine Lceyb     
adj.犬的,犬科的
参考例句:
  • The fox is a canine animal.狐狸是犬科动物。
  • Herbivorous animals have very small canine teeth,or none.食草动物的犬牙很小或者没有。
6 determined duszmP     
adj.坚定的;有决心的
参考例句:
  • I have determined on going to Tibet after graduation.我已决定毕业后去西藏。
  • He determined to view the rooms behind the office.他决定查看一下办公室后面的房间。
TAG标签: cancer skin sound melanoma
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