文章来源:未知 文章作者:meng 发布时间:2010-02-02 00:31 字体: [ ]  进入论坛

A new therapeutic治疗的 made from tobacco plants has been shown to arrest逮捕,阻止 West Nile virus infection, according to a new study by Arizona State University scientist Qiang Chen and his colleagues. Chen, a researcher at Arizona State University's Biodesign Institute and professor in the PolyTechnic2 Campus' College of Technology and Innovation, is the first to demonstrate a plant-derived3 treatment to successfully combat West Nile virus after exposure and infection. The research appears in this week's issue of the Proceedings4 of the National Academy of Sciences (advanced online edition).

There are currently no available vaccines疫苗 against West Nile, nor effective therapeutics for human use, so the current findings are a considerable advancement6 and may offer the best hope thus far迄今,现在为止 that the West Nile virus infection can be stopped, even several days after viral infection.

West Nile virus has made alarming inroads损害,侵犯 in North America, causing disease outbreaks throughout the U.S., as well as in areas of Canada, Mexico, the Caribbean and South America. Elderly individuals and those with depressed7 immunity8 are particularly vulnerable to易受……的攻击 West Nile, a mosquito-borne illness which can cause a potentially lethal致命的 inflammation of the brain.

Chen's group demonstrated the versatility用途广泛,多功能性 of plant-based biotechnology. "The goal of this research was twofold," said Chen. "First, we wanted to show proof-of- concept, demonstrating that plant-made antibodies抗体 can work as effective post-exposure therapeutics. Secondly11, we've sought to develop a therapeutic1 which can be made inexpensively so that the health care systems in developing countries can afford it."

Issues of affordability支付能力,负担能力 for such antibody-based treatments are central to the challenge, Chen stresses, with the costs for development of a traditional pharmaceutical13 mammalian哺乳类的 cell line production facility often running into the tens of millions of dollars. Besides being inexpensive, plants offer other advantages. Mammalian cell lines may run the risk of harboring animal pathogens病原体,致病菌 such as viruses or infectious protein agents known as prions朊病毒,小蛋白粒, not found in plants. Plants also allow production of pharmaceutical products to be easily scaled up to whatever quantities are required. "With mammalian cells systems, the physical size of the bioreactor生物反应器 is limiting," said Chen, "whereas with plants, we can just plant another acre英亩,土地."

The study examined antibodies against West Nile virus derived from mammalian cell lines and compared their effectiveness with those extracted from plants. The plants used to produce the antibodies are a relative of common tobacco, a member of the Solanceae family of plants, which produce abundant leaves for harvesting material and are also prolific14多产的,丰富的 seed producers. Seven days after the introduction of antibody genes15 into plants, the leaves are harvested, homogenized and purified to remove extraneous外来的 material.


1 therapeutic sI8zL     
  • Therapeutic measures were selected to fit the patient.选择治疗措施以适应病人的需要。
  • When I was sad,music had a therapeutic effect.我悲伤的时候,音乐有治疗效力。
2 polytechnic g1vzw     
  • She was trained as a teacher at Manchester Polytechnic.她在曼彻斯特工艺专科学校就读,准备毕业后做老师。
  • When he was 17,Einstein entered the Polytechnic Zurich,Switzerland,where he studied mathematics and physics.17岁时,爱因斯坦进入了瑞士苏黎士的专科学院,学习数学和物理学。
3 derived 6cddb7353e699051a384686b6b3ff1e2     
vi.起源;由来;衍生;导出v.得到( derive的过去式和过去分词 );(从…中)得到获得;源于;(从…中)提取
  • Many English words are derived from Latin and Greek. 英语很多词源出于拉丁文和希腊文。 来自《简明英汉词典》
  • He derived his enthusiasm for literature from his father. 他对文学的爱好是受他父亲的影响。 来自《简明英汉词典》
4 proceedings Wk2zvX     
  • He was released on bail pending committal proceedings. 他交保获释正在候审。
  • to initiate legal proceedings against sb 对某人提起诉讼
5 vaccines c9bb57973a82c1e95c7cd0f4988a1ded     
疫苗,痘苗( vaccine的名词复数 )
  • His team are at the forefront of scientific research into vaccines. 他的小组处于疫苗科研的最前沿。
  • The vaccines were kept cool in refrigerators. 疫苗放在冰箱中冷藏。
6 advancement tzgziL     
  • His new contribution to the advancement of physiology was well appreciated.他对生理学发展的新贡献获得高度赞赏。
  • The aim of a university should be the advancement of learning.大学的目标应是促进学术。
7 depressed xu8zp9     
  • When he was depressed,he felt utterly divorced from reality.他心情沮丧时就感到完全脱离了现实。
  • His mother was depressed by the sad news.这个坏消息使他的母亲意志消沉。
8 immunity dygyQ     
  • The law gives public schools immunity from taxation.法律免除公立学校的纳税义务。
  • He claims diplomatic immunity to avoid being arrested.他要求外交豁免以便避免被捕。
9 lethal D3LyB     
  • A hammer can be a lethal weapon.铁锤可以是致命的武器。
  • She took a lethal amount of poison and died.她服了致命剂量的毒药死了。
10 versatility xiQwT     
  • Versatility is another of your strong points,but don't overdo it by having too many irons in the fire.你还有一个长处是多才多艺,但不要揽事太多而太露锋芒。
  • This versatility comes from a dual weather influence.这种多样性是由于双重的气候影响而形成的。
11 secondly cjazXx     
  • Secondly,use your own head and present your point of view.第二,动脑筋提出自己的见解。
  • Secondly it is necessary to define the applied load.其次,需要确定所作用的载荷。
12 affordability b765fd6126db9695d9d5b74d209e7527     
  • Performance-Based Logistics Affordability: Can We Afford Categorical Conversion to Performance-Based Acquisition? 基于性能的后期的可承受性:能否担负得起向基于性能的采办的无条件的转变?
  • There would be no crisis of affordability, as't for food or clothing. 就想食物与服装一样,因为供给没有危机。
13 pharmaceutical f30zR     
  • She has donated money to establish a pharmaceutical laboratory.她捐款成立了一个药剂实验室。
  • We are engaged in a legal tussle with a large pharmaceutical company.我们正同一家大制药公司闹法律纠纷。
14 prolific fiUyF     
  • She is a prolific writer of novels and short stories.她是一位多产的作家,写了很多小说和短篇故事。
  • The last few pages of the document are prolific of mistakes.这个文件的最后几页错误很多。
15 genes 01914f8eac35d7e14afa065217edd8c0     
n.基因( gene的名词复数 )
  • You have good genes from your parents, so you should live a long time. 你从父母那儿获得优良的基因,所以能够活得很长。 来自《简明英汉词典》
  • Differences will help to reveal the functions of the genes. 它们间的差异将会帮助我们揭开基因多种功能。 来自英汉非文学 - 生命科学 - 生物技术的世纪
16 extraneous el5yq     
  • I can choose to ignore these extraneous thoughts.我可以选择无视这些外来的想法。
  • Reductant from an extraneous source is introduced.外来的还原剂被引进来。
TAG标签: tobacco virus therapeutic