肠道亦分种类
文章来源:未知 文章作者:enread 发布时间:2011-04-21 03:29 字体: [ ]  进入论坛
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In the future, when you walk into a doctor's surgery or hospital, you could be asked not just about your allergies1 and blood group, but also about your gut2 type. Scientists at the European Molecular3 Biology Laboratory (EMBL) in Heidelberg, Germany, and collaborators in the international MetaHIT consortium, have found that humans have 3 different gut types. The study, published today in Nature, also uncovers microbial genetic4 markers that are related to traits like age, gender5 and body-mass index. These bacterial6 genes7 could one day be used to help diagnose and predict outcomes for diseases like colo-rectal cancer, while information about a person's gut type could help inform treatment. We all have bacteria in our gut that help digest food, break down toxins8, produce some vitamins and essential amino acids(氨基酸) , and form a barrier against invaders9. But the composition of that microbial community – the relative numbers of different kinds of bacteria – varies from person to person.

"We found that the combination of microbes in the human intestine10(肠) isn't random," says Peer Bork, who led the study at EMBL: "our gut flora11(植物) can settle into three different types of community – three different ecosystems12, if you like."

Bork and colleagues first used stool samples to analyse the gut bacteria of 39 individuals from three different continents (Europe, Asia and America), and later extended the study to an extra 85 people from Denmark and 154 from America. They found that all these cases could be divided into three groups, based on which species of bacteria occurred in high numbers in their gut: each person could be said to have one of three gut types, or enterotypes.

The scientists don't yet know why people have these different gut types, but speculate that they could be related to differences in how their immune systems distinguish between 'friendly' and harmful bacteria, or to different ways of releasing hydrogen waste from cells.

Like blood groups, these gut types are independent of traits like age, gender, nationality and body-mass index. But the scientists did find for example, that the guts13 of older people appear to have more microbial genes involved in breaking down carbohydrates14(碳水化合物) than those of youngsters, possibly because as we age we become less efficient at processing those nutrients15, so in order to survive in the human gut, bacteria have to take up the task.

"The fact that there are bacterial genes associated with traits like age and weight indicates that there may also be markers for traits like obesity16 or diseases like colo-rectal cancer," Bork says, "which could have implications for diagnosis17 and prognosis."

If this proves to be the case, when diagnosing or assessing the likelihood of a patient contracting a particular disease, doctors could look for clues not only in the patient's body but also in the bacteria that live in it. And after diagnosis, treatment could be adapted to the patient's gut type to ensure the best results.



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1 allergies 2c527dd68e63f119442f4352f2a0b950     
n.[医]过敏症;[口]厌恶,反感;(对食物、花粉、虫咬等的)过敏症( allergy的名词复数 );变态反应,变应性
参考例句:
  • Food allergies can result in an enormous variety of different symptoms. 食物过敏会引发很多不同的症状。 来自辞典例句
  • Let us, however, examine one of the most common allergies; hayfever. 现在让我们来看看最常见的变态反应的一种--枯草热。 来自辞典例句
2 gut MezzP     
n.[pl.]胆量;内脏;adj.本能的;vt.取出内脏
参考例句:
  • It is not always necessary to gut the fish prior to freezing.冷冻鱼之前并不总是需要先把内脏掏空。
  • My immediate gut feeling was to refuse.我本能的直接反应是拒绝。
3 molecular mE9xh     
adj.分子的;克分子的
参考例句:
  • The research will provide direct insight into molecular mechanisms.这项研究将使人能够直接地了解分子的机理。
  • For the pressure to become zero, molecular bombardment must cease.当压强趋近于零时,分子的碰撞就停止了。
4 genetic PgIxp     
adj.遗传的,遗传学的
参考例句:
  • It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
  • Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。
5 gender slSyD     
n.(生理上的)性,(名词、代词等的)性
参考例句:
  • French differs from English in having gender for all nouns.法语不同于英语,所有的名词都有性。
  • Women are sometimes denied opportunities solely because of their gender.妇女有时仅仅因为性别而无法获得种种机会。
6 bacterial dy5z8q     
a.细菌的
参考例句:
  • Bacterial reproduction is accelerated in weightless space. 在失重的空间,细菌繁殖加快了。
  • Brain lesions can be caused by bacterial infections. 大脑损伤可能由细菌感染引起。
7 genes 01914f8eac35d7e14afa065217edd8c0     
n.基因( gene的名词复数 )
参考例句:
  • You have good genes from your parents, so you should live a long time. 你从父母那儿获得优良的基因,所以能够活得很长。 来自《简明英汉词典》
  • Differences will help to reveal the functions of the genes. 它们间的差异将会帮助我们揭开基因多种功能。 来自英汉非文学 - 生命科学 - 生物技术的世纪
8 toxins 18c3f40d432ba8dc33bad8fb82873ea8     
n.毒素( toxin的名词复数 )
参考例句:
  • The seas have been used as a receptacle for a range of industrial toxins. 海洋成了各种有毒工业废料的大容器。
  • Most toxins are naturally excreted from the body. 大部分毒素被自然排出体外。 来自《简明英汉词典》
9 invaders 5f4b502b53eb551c767b8cce3965af9f     
入侵者,侵略者,侵入物( invader的名词复数 )
参考例句:
  • They prepared to repel the invaders. 他们准备赶走侵略军。
  • The family has traced its ancestry to the Norman invaders. 这个家族将自己的世系追溯到诺曼征服者。
10 intestine rbpzY     
adj.内部的;国内的;n.肠
参考例句:
  • This vitamin is absorbed through the walls of the small intestine.这种维生素通过小肠壁被吸收。
  • The service productivity is the function,including external efficiency,intestine efficiency and capacity efficiency.服务业的生产率是一个包含有外部效率、内部效率和能力效率的函数。
11 flora 4j7x1     
n.(某一地区的)植物群
参考例句:
  • The subtropical island has a remarkably rich native flora.这个亚热带岛屿有相当丰富的乡土植物种类。
  • All flora need water and light.一切草木都需要水和阳光。
12 ecosystems 94cb0e40a815bea1157ac8aab9a5380d     
n.生态系统( ecosystem的名词复数 )
参考例句:
  • There are highly sensitive and delicately balanced ecosystems in the forest. 森林里有高度敏感、灵敏平衡的各种生态系统。 来自《简明英汉词典》
  • Madagascar's ecosystems range from rainforest to semi-desert. 马达加斯加生态系统类型多样,从雨林到半荒漠等不一而足。 来自辞典例句
13 guts Yraziv     
v.狼吞虎咽,贪婪地吃,飞碟游戏(比赛双方每组5人,相距15码,互相掷接飞碟);毁坏(建筑物等)的内部( gut的第三人称单数 );取出…的内脏n.勇气( gut的名词复数 );内脏;消化道的下段;肠
参考例句:
  • I'll only cook fish if the guts have been removed. 鱼若已收拾干净,我只需烧一下即可。
  • Barbara hasn't got the guts to leave her mother. 巴巴拉没有勇气离开她妈妈。 来自《简明英汉词典》
14 carbohydrates 001f0186d1ea717492c413ca718f2635     
n.碳水化合物,糖类( carbohydrate的名词复数 );淀粉质或糖类食物
参考例句:
  • The plant uses the carbohydrates to make cellulose. 植物用碳水化合物制造纤维素。 来自《简明英汉词典》
  • All carbohydrates originate from plants. 所有的碳水化合物均来自植物。 来自辞典例句
15 nutrients 6a1e1ed248a3ac49744c39cc962fb607     
n.(食品或化学品)营养物,营养品( nutrient的名词复数 )
参考例句:
  • a lack of essential nutrients 基本营养的缺乏
  • Nutrients are absorbed into the bloodstream. 营养素被吸收进血液。 来自《简明英汉词典》
16 obesity Dv1ya     
n.肥胖,肥大
参考例句:
  • One effect of overeating may be obesity.吃得过多能导致肥胖。
  • Sugar and fat can more easily lead to obesity than some other foods.糖和脂肪比其他食物更容易导致肥胖。
17 diagnosis GvPxC     
n.诊断,诊断结果,调查分析,判断
参考例句:
  • His symptoms gave no obvious pointer to a possible diagnosis.他的症状无法作出明确的诊断。
  • The engineer made a complete diagnosis of the bridge's collapse.工程师对桥的倒塌做一次彻底的调查分析。
TAG标签: genetic human gut
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