13-09-22 Scientists at the Stanford University School of Medicine have shown how a protein fragment known as beta- amyloid(淀粉体) , strongly implicated in Alzheimer's disease, begins destroying synapses(突触) before it clumps into plaques that lead to n...
13-09-22 Mayo Clinic researchers have shown that a specific protein pair may be a successful prognostic(预兆) biomarker for identifying smoking-related lung cancers. The protein -- ASCL1 -- is associated with increased expression of the RET oncogene, a par...
13-09-18 Each cell in an organism has a sensor that measures the health of its internal environment. This alarm is found in the endoplasmic reticulum ( ER内质网 ), which is able to sense cellular stress and trigger either rescue responses or the death of the...
13-09-18 Separating target molecules in biological samples is a critical part of diagnosing and detecting diseases. Usually the target and probe molecules are mixed and then separated in batch processes that require multiple pipetting(移液,吸量) , tube wa...
13-09-13 Researchers at the Pediatric Diabetes Research Center (PDRC) at the University of California, San Diego School of Medicine have shown that the pancreatic(胰腺的) protein Nkx6.1 -- a beta-cell enriched transcription factor -- is essential to mainta...
13-09-04 People with epilepsy(癫痫) could be helped by new research into the way a key molecule controls brain activity during a seizure. Researchers have identified the role played by of a protein -- called BDNF -- and say the discovery could lead to new...
13-07-04 Neurodegenerative(神经变性的) diseases such as Alzheimer's could be better understood thanks to insight into proteins linked to such conditions, a study suggests. Scientists studying thread-like chains of protein -- called amyloid(淀粉体) fibres...
13-06-28 Reporting this month in Molecular Microbiology, Peter Chien and colleagues at the University of Massachusetts Amherst describe using a combination of biochemistry and mass spectrometry(质谱分析法) to trap scores of new candidate substrates of the...
13-06-28 Scientists at the University of California, Santa Cruz, have trapped the ribosome(核糖体) , a protein-building molecular machine essential to all life, in a key transitional state that has long eluded(逃避) researchers. Now, for the first time,...
13-06-16 Scientists at the University of Liverpool have shed new light on how diving mammals, such as the sperm whale, have evolved to survive for long periods underwater without breathing. The team identified a distinctive molecular signature of the oxygen-...