高脂饮食可延缓大脑衰老

New Danish-led research suggests that signs of brain aging can be postponed² in mice if placed on a high-fat diet. In the long term, this opens the possibility of treatment of children suffering from premature³ aging and patients with Alzheimer's and Parkinson's disease. The research project is headed by the Center for Healthy Aging, University of Copenhagen and the National Institute of Health. When we get older, defects begin to develop in our nervous system, our brain loses some of its intellectual capacity, and the risk of developing diseases such as Parkinson's and Alzheimer's increases. Alzheimer's disease is currently the fastest-growing age-related disease.

 

Throughout our lives, it is important that our cells -- to the extent possible -- keep our DNA⁴ undamaged, and, therefore, the cells have a system that repairs the damage that occurs all the time. Humans age when the repair system ceases to function. In diseases such as Alzheimer's, the researchers also see damage to the DNA

 

A new research project headed by the Center for Healthy Aging, University of Copenhagen and the National Institute of Health has studied mice having a defect in their DNA repair system. In humans, this defect causes the disorder⁵ Cockayne syndrome⁶, where patients prematurely⁷ age as children and die at an age of 10-12 years. The study shows that placing a mouse model of Cockayne syndrome on a high-fat diet will postpone¹ aging processes such as impaired⁸ hearing and weight loss.

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